Sialidase of rat liver and kidney.

نویسندگان

  • S Mahadevan
  • J C Nduguba
  • A L Tappel
چکیده

Sialidase is shown to be localized in the lysosomes of rat liver and kidney. The pH optimum with sialyllactose as substrate is 4.4, and with glycoproteins is 4.0. The enzyme is not affected by many divalent metal ions, ethylenediaminetetraacetate, or fi-chloromercuribenzoate, and is active against many glycoproteins and gangliosides, indicating its possible role in their intracellular digestion.

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عنوان ژورنال:
  • The Journal of biological chemistry

دوره 242 19  شماره 

صفحات  -

تاریخ انتشار 1967